Evidence

Reprocessing of PPE Garments for re-use by clinical staff – Vaporised Hydrogen Peroxide method

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Background

Within the context of PPE shortages during the coronavirus pandemic, University Hospital Southampton NHS Foundation Trust tested the feasibility of reprocessing used garments
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Method

Inivos’ process of vaporised hydrogen peroxide (VHP) was applied to laundered garments, to test its effectiveness in decontaminating single-use PPE items for re-use
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Results

The process achieved satisfactory standards of disinfection, using organisms considered, on current data, to be worst-case surrogates for SARS-CoV-2
Report

Reprocessing of PPE Garments for re-use by clinical staff – Vaporised Hydrogen Peroxide method

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>5 log reduction of microorganisms after an MRSA outbreak on a gastroenterology ward

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Background

Colonisation with methicillin-resistant Staphylococcus aureus is a risk factor for subsequent MRSA infections in hospital patients.
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Method

Ultra-V™ UV-C system was used to decontaminate a gastroenterology ward infected with MRSA.
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Results

After manual cleaning was not effective, the Ultra-V™ system was used. Swabs taken afterwards came back negative for MRSA.
Ultra-V UV-C decontamination case study Buckinghamshire Healthcare NHS

Environment MRSA in clinical areas and the efficacy of Ultra-V™ in an outbreak situation

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Contamination level reduced by 97% with a fraction of the room downtime using Ultra-V™

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Background

Ultra-V™ was used to assess the efficacy of UV-C decontamination on surfaces both directly and indirectly exposed to UV-C.

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Method

Manual cleaning was performed on chosen surfaces followed by sample collection and decontamination using UV-C

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Results

After UV-C decontamination the number of total viability counts was reduced by 97% from levels after initial manual cleaning

c-diff contamination reduced by 97%

Evaluation of Ultra-V™ decontamination as an adjunctive to manual cleaning at Barnsley Hospital

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Impact of cleaning and other interventions on the reduction of hospital-acquired C. diff infections assessed using a breakpoint model

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Background

Hospital-acquired C.difficile is one of the biggest concerns in healthcare settings. Effective infection control interventions can be difficult to monitor.
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Method

The infection control data from two hospitals in England was used for statistical breakpoint analysis.
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Results

While a variety of interventions are needed to control C.diff, deep cleaning incorporating HPV decontamination is most effective in reducing CDI rates.
hospital acquired infection c-diff reduction

Impact of cleaning and other interventions on the reduction of hospital-acquired C. diff infections in two hospitals in England assessed using a breakpoint model.

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Deprox™ decontamination and improved cleaning process reduce C. diff by 92%

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Background

Aim to substantiate the long-term effectiveness of in a stroke rehabilitation unit of deep cleaning and hydrogen peroxide decontamination (HPD).
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Method

Environmental sampling taken before and after deep cleaning; immediately following HPD; and two further occasions.

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Results

HPD, after deep cleaning with a detergent/chlorine agent, was highly effective for removing C. diff contamination.

Leeds-hospital

Effectiveness of deep cleaning followed by hydrogen peroxide decontamination during high Clostridium difficile infection incidence.

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98% reduction in contamination levels and a cleaning process 8 times faster

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Background

Ultra-V™ was chosen to decontaminate the environment during a construction project within the Walsall Healthcare hospital.

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Method

Manual cleaning was performed and samples collected to measure total viability count (TVC). Afterwards, Ultra-V™ decontamination was carried out and new samples were taken.

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Results

A strong presence of TVC was still found after manual cleaning, whilst after Ultra-V™ decontamination the levels of TVC were 98% lower.

Ultraviolet decontamination of hospital acquired infections

Walsall Hospital trials Ultra-UV™ and reduces the time spent on decontaminating a new build ward project.

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Deprox™ decontamination and improved cleaning process reduce MRO acquisition by 92%

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Background

Multiresistant organisms (MRO) at were on the increase. An action plan was formed using improved manual cleaning and Hydrogen Peroxide Vapour.

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Method

Sutherland Hospital ICU improved PPE requirements and implemented Deprox™ into their decontamination programme.

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Results

After using Deprox™, the ICU experienced significantly lower MRO cases and  reduced the occupied-bed number by over 90%.

hospital infection control using Deprox reduces acquisition rates by 92%

The Sutherland Hospital Intensive Care Unit developed an action plan in response to increases in the level of multi-resistant organisms.

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95% reduction in contamination in a study of 58 hospital rooms over 12 months

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Background

A study to determine the efficacy of using hydrogen peroxide vapour for decontamination of hospital side rooms.

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Method

Large environmental sampling for C.difficile was performed before deep cleaning with chlorine agents and again after Deprox™ HPV.

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Results

Deprox™ cleaning reduced contamination levels by 95% from the levels observed after deep cleaning.

cambridge-university-hospital

The effectiveness of deep cleaning followed by hydrogen peroxide decontamination across 58 rooms at Addenbrooke's Hospital

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Hydrogen Peroxide Vapour decontamination significantly reduces enteric bacteria in Neonatal Units

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Background

Drug-resistant, Gram-negative bacteria (DRGNB) infection rates are higher in Neonatal Units (NNUs) than in any other hospital setting.

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Method

Inivos’ hydrogen peroxide vapour (HPV) disinfection robot was used to disinfect three NNUs over two days. Swabs were taken before and after HPV use. 

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Results

The amount of enteric bacteria was significantly reduced across the three NNUs after HPV decontamination.

Birmingham Childerns Hospital Poster

Impact of HPV Decontamination on DRGNB rates in NICU Unit

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Reducing cases of Clostridium Difficile by identifying a 'front end' and decontaminating with HPV

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Background

Stoke Mandeville Hospital sought to reduce transmission of C. difficile by identifying a common entry point and using vapourised hydrogen peroxide (VHP) to decontaminate.

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Method

A ‘front-end’ for C.diff patients was identified, isolated and decontaminated using Inivos’ VHP disinfection robot. This including patient equipment and ameliorated IPC measures.

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Results

The rate of infection of C.diff in Stoke Mandeville Hospital decreased after the identification of the common entry point and decontamination using VHP.

Buckinghamshire Healthcare Front-end Poster

Decontamination of the hospital ‘front-end’ using hydrogen peroxide vapour is an effective method to reduce Clostridium difficile infection rates within the hospital

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Using a RAG-rated system and HPV decontamination to reduce rates of C.Diff

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Background

The use of hydrogen peroxide vapour (HPV) decontamination and the impact on rates of clostridium difficile was evaluated.

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Method

Calderdale and Huddersfield NHS Foundation Trust incorporated Inivos’ HPV disinfection robot into their cleaning routine, introduced a RAG-rated cleaning system and measured.

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Results

Post-admission C.diff cases reduced significantly as a result of HPV decontamination and the risk-based approach  provided by the RAG-rated cleaning system.

Calderdale Huddersfiled Poster

Enhanced Cleaning Intervention in two DGH Acute Hospitals in the North East Region

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HPV and enhanced manual cleaning terminates the transmission of VRE

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Background

Infections of vancomycin resistant enterococcus (VRE) in Australian hospitals had been on the increase.  Repeated introduction of VRE in Fremantle Hospital had seen a spread of VRE across their wards as a result.

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Method

The hospital tested the efficacy of Inivos’ hydrogen peroxide vapour (HPV) system in preventing the environmental transmission of VRE in high risk units (HRU) and screened patients in HRU on admission and regularly thereafter.

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Results

Using the HPV system alongside enhanced manual cleaning in toilet areas on a ward, terminated spread where it had, before, been known to have increased.

Fremantle Hospital Poster

Clusters of vancomycin resistant enterococcus (VRE) carriage identified through a surveillance program in a tertiary teaching hospital

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UV-C decontamination is an effective decontamination method in areas undergoing construction

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Background

Infectious outbreaks have been connected with ongoing building works in hospitals. Reducing bioburden in the patient environment is linked with reducing the risks for hospital acquired infections.

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Method

Rooms were tested before and after decontamination using Ultra-V UV-C technology during ongoing construction on a general medical ward.

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Results

UV-C decontamination achieved a significant level of reduction of microorganisms detected on the surfaces, without the requirement for vapour-impermeable sealing.

Morecombe Bay Poster

Decontamination of general medical ward facilities with UV-C during construction in Royal Lancaster Infirmary

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A deep cleaning programme incorporating UV-C decontamination reduces C.diff significantly

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Background

North West Anglia Trust focussed on implementing new IPC strategies to reduce rates of Clostridium difficile, one of the main Hospital Acquired Infections (HAI) in the UK.

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Method

A deep clean programme using Ultra-V disinfection robot technology by Inivos was implemented from April 2015 and C.diff cases were compared before and after.

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Results

Using Ultra-V as part of the deep clean programme, rates of C.diff in 2016 fell to their lowest levels since reports dating back to 2009.

Peterborough Poster ECCMID

Implementation and regular usage of Ultra-V UV-C is required to reduce infection rates of Clostridium difficile within hospital environment

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Ultra-V is highly effective in eliminating bacteria, and especially in cystic fibrosis clinics

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Background

Patients with cystic fibrosis are more prone to infections, potentially leading to longer hospital stays as a result of acquiring an infection in hospital.

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Method

The effectiveness of Ultra-V UV-C was tested against disinfection with a chlorine-containing solution in 11 rooms on a cystic fibrosis ward, after the discharge of infected patients.

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Results

The Ultra-V UV-C decontamination system had a significantly stronger effect on microorganisms compared to manual cleaning, and completely eliminated microorganisms in the majority of cases.

Royal Papworth Poster

Microbiological evaluation of UV disinfection effectiveness in a specialist cystic fibrosis clinic

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UV-C decontamination is an effective adjunct to manual cleaning in reducing risk of infection

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Background

A study was conducted by Royal Wolverhampton to explore the integration of UV-C as an adjunctive cleaning practice.

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Method

Inivos’ Ultra-V UV-C disinfection robot was used following manual cleaning in 18 vacated rooms across a period of 8 weeks. Sampling was undertaken at 24 sites in each room and results expressed as colony forming units (CFU).

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Results

The mean CFU post-use of Ultra-V was much reduced compared to post-manual cleaning and significantly so when compared to pre-manual cleaning.

Royal Wolverhampton Poster

Can room decontamination with ultra violet (UV-C) light be a useful addition to healthcare cleaning processes- a small study of its use in a UK hospital setting

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Hydrogen peroxide vapour is an effective decontamination solution to reducing CPE

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Background

Public Health England recommendations on identifying and isolating patients on admission in an effort to reduce cases of CPE were not practicable for University Hospital of South Manchester as cases were too numerous.

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Method

Alongside other screening methods, Inivos’ HPV system was applied to decontaminate the environment following discharge or transfer of each patient known to be infected with CPE.

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Results

With regard to preventing cases of CPE, Inivos’ HPV system was a highly effective decontamination mechanism in this clinical setting.

South Manchester Poster

Screening AND Cleaning: How University Hospital of South Manchester reduced the number of in-patients being identified with CPE

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Routine screening and hydrogen peroxide vapour decontamination eliminates transmission of MRSA

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Background

Westmead Hospital, Sydney, were concerned about the outbreak of MRSA on their NICU ward and environmental contamination.

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Method

Routine screening of mothers and babies was introduced alongside the use of Inivos hydrogen peroxide vapour (HPV) disinfection robot.

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Results

Use of Inivos’ HPV technology effectively eliminated transmission of the virulent MRSA outbreak strain.

Westmead Hospital Poster

Innovations for MRSA control in a Neonatal Intensive Care Unit (NICU) – MRSA control bundle

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Ultra-V has a fast decontamination time and is effective at reducing microorganisms

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Background

The time taken to decontaminate side rooms at Wye Valley NHS Trust proved challenging with the pressures it had on bed use.

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Method

The efficacy of the Ultra-V UV-C disinfection robot has the potential to decontaminate rooms in 15-30 minutes and was evaluated in 20 rooms, with samples taken.

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Results

The average total viable count (TVC) per contact plate before cleaning was 27.4; after cleaning 19.3; and after the Ultra-V system 2.3.

Evaluation of the Ultra-V trade; (ultraviolet) decontamination system as an adjunct to cleaning in a [...]

Evaluation of the Ultra-V (ultraviolet) decontamination system as an adjunct to cleaning in a district general hospital

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